Lily Hui-Ching WangPersonal data of - College of Life Science, National Tsing Hua University

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Name	Lily Hui-Ching Wang
Fax	03-5715934
Personal website	https://sites.google.com/site/lilywangslab/

Category	Full-Time
Title	Associate Professor
單位別	Institute of Molecular and Cellular Biology / Interdisciplinary Program of Life Science / Department of Medical Science
Discipline	Cell biology, Molecular Biology, Tumor Biology
Research expertise	Cell Biology, Live Cell Imaging, Mitosis, Hepatitis B virus, Liver Cancer

Recent Publications
Year	Publication	Author
2015	Christian F. Nielsen, Diana Huttner, Anna H. Bizard, Seiki Hirano, Tian-Neng Li, Timea Palmai-Pallag, Victoria A. Bjerregaard, Ying Liu, Erich A. Nigg, Lily Hui-Ching Wang & Ian D. Hickson,2015,PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis,Nature Communications, (SCI)	Lily Hui-Ching Wang
2015	Yi-Hsuan Hsieh, Yu-Ying Chang, Ih-Jen Su, Chia-Jui Yen, Yi-Ru Liu, Ren-Jei Liu, Wen-Chuan Hsieh, Hung-Wen Tsai, Lily Hui-Ching Wang, Wenya Huang,2015,Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double strand break repair and leads to genome instability in hepatocarcinogenesis,Journal of Pathology, (SCI)	Lily Hui-Ching Wang
2015	Chen CJ, Shih CH, Chang YJ, Hong SJ, Li TN, Wang LH, Chen L.,2015,SH2B1 and IRSp53 Proteins Promote the Formation of Dendrites and Dendritic Branches,Journal of Biological chemistry,290,pp6010-6021 (SCI)	Lily Hui-Ching Wang
2015	Lyu-Han Wang, Chia-Jui Yen, Tian-Neng Li, Sabine Elowe, Wen-Ching Wang, Lily Hui-Ching Wang,2015,Sgo1 is a potential therapeutic target for hepatocellular carcinoma,Oncotarget,6,4,pp2023-2033 (SCI)	Lily Hui-Ching Wang
2015	Szu-Ting Lin, Eugenie Wong Soon May, Jo-Fan Chang, Ren-Yu Hu, Lily Hui-Ching Wang, Hong-Lin Chan ,2015,PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma,Cellular and Molecular Life Sciences, (SCI)	Lily Hui-Ching Wang
2014	Ih-Jen Su, Lily Hui-Ching Wang, Wen-Chuan Hsieh, Han-Chieh Wu, Chiao-Fang Teng, Hung-Wen Tsai, Wenya Huang,2014,The emerging role of hepatitis B virus Pre-S2 deletion mutant proteins in HBV tumorigenesis,Journal of biomedical science,21,1,pp98- (SCI)	Lily Hui-Ching Wang
2014	Kung-Chao Chang, Yao Chang, Lily Hui-Ching Wang, Hung-Wen Tsai, Wenya Huang, Ih-Jen Su,2014,Pathogenesis of virus-associated human cancers: Epstein–Barr virus and hepatitis B virus as two examples,Journal of the Formosan Medical Association,113,9,pp581-590 (SCI)	Lily Hui-Ching Wang
2014	Shin-Yi Du, Hung-Jung Wang, Hsin-Hung Cheng, Sheng-De Chen, Lily Hui-Ching Wang, Wen-Ching Wang,2014,Cholesterol glucosylation by Helicobacter pylori delays internalization and arrests phagosome maturation in macrophages,Journal of Microbiology, Immunology and Infection, (SCI)	Lily Hui-Ching Wang
2014	Han-Chieh Wu, Hung-Wen Tsai, Chiao-Fang Teng, Wen-Chuan Hsieh, Yi-Chi Lin, Lily Hui-Ching Wang, Quan Yuan, Ih-Jen Su,2014,Ground glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis,Human Pathology, (SCI)	Lily Hui-Ching Wang
2013	Biebricher A., Hirano S., Enzlin J., Wiechens N., Streicher W., Liu Y., Huttner D., Wang LH., Nigg EA., Owen-Hughes T., Peterman E., Wuite G., and Hickson I.,2013,PICH: a DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA,Molecular Cell, (SCI)	Lily Hui-Ching Wang
2013	Chang KC, Chang Y, Wang LH, Tsai HW, Huang W, Su IJ,2013,Pathogenesis of viruses-associated human cancers: Epstein-Barr virus and hepatitis B virus as two examples,J Formos Med Assoc, (SCI)	Lily Hui-Ching Wang
2013	Yi-Ru Liu, Sheng-Yen Huang, Jen-Yang Chen, and Lily Hui-Ching Wang,2013,Microtubule depolymerization activates the Epstein-Barr virus lytic cycle through protein kinase C pathways in nasopharyngeal carcinoma cells,Journal of General Virology, (SCI)	Lily Hui-Ching Wang
2012	Yu GY, He G, Li CY, Tang M, Grivennikov S, Tsai WT, Wu MS, Hsu CW, Tsai Y, Wang LH, Karin M,2012,Hepatic Expression of HCV RNA-Dependent RNA Polymerase Triggers Innate Immune Signaling and Cytokine Production,Molecular Cell, (SCI)	Lily Hui-Ching Wang
2012	Hung-Ju Shih, Kang-Lin Chu, Meng-Hsun Wu, Pei-Hsuan Wu, Wei-Wen Chang, Jan-Show Chu, Lily Hui-Ching Wang, Hideki Takeuchi, Toru Ouchi, and Hsin-Ling Hsu,2012,The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities,Cell Cycle,11,5,pp934-52 (SCI)	Lily Hui-Ching Wang
2012	Wang LH, Huang W, Lai MD, Su IJ,2012,Aberrant cyclin A expression and centrosome overduplication induced by hepatitis B virus Pre-S2 mutants and its implication in hepatocarcinogenesis,Carcinogenesis, (SCI)	Lily Hui-Ching Wang
2011	Hung JH, Teng YN, Wang LH, Su IJ, Wang CC, Huang W, Lee KH, Lu KY, Wang LH,2011,Induction of bcl-2 expression by hepatitis B virus pre-s2 mutant large surface protein resistance to 5-Fluorouracil treatment in huh-7 cells,PLoS One,6,12,ppe28977- (SCI)	Lily Hui-Ching Wang
2010	Hubner, N.C., Wang, L.H.C., Kaulich, M., Descombes, P., Poser, I. and Nigg, E. A. ,2010,Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs,Chromosoma,119,2,pp149-165 (SCI)	Lily Hui-Ching Wang
2010	Wang L HC, Mayer B, Stemmann O, and Nigg EA.,2010,Centromere DNA decatenation depends on separase activation and is required for mammalian cell division,Journal of Cell Science*,123,5,pp806-813	Lily Hui-Ching Wang
2008	2010,Su IJ, Wang HC, Wu HC, Huang WY. Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection. Review Article. J Gastroenterol Hepatol. 2008 23(8 Pt 1):1169-74,J Gastroenterol Hepatol.,23,pp1169-1174	Lily Hui-Ching Wang
2008	2008,Wang L HC, Schwarzbraun T, Speicher MR, Nigg EA. Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma 2008, 117(2):123-35,Chromosoma,117,pp123-135	Lily Hui-Ching Wang
2007	2007,Hsieh YH, Su IJ, Wang HC, Tsai JH, Huang YJ, Chang WW, Lai MD, Lei HY, Huang W. Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclindependent kinase inhibitor p27Kip1 through c-Jun activation domain-binding protein 1. Molecular Cancer Research 2007 10: 2063-72,Molecular Cancer Research,10,pp2063-2072	Lily Hui-Ching Wang
2006	2006,Wang HC, Lai MD, Huang W, Su IJ. Hepatitis B Virus Pre-S Mutants, ER stress and Hepatocarcinogenesis. Review Article. Cancer Science 2006, 97:683-688,Cancer Science,97,pp683-688	Lily Hui-Ching Wang
2005	Wang HC, Chang WT, Chang WW, Wu HC, Huang W, Lei HY, Lai MD, Fausto N, Su IJ,2005,Wang HC, Chang WT, Chang WW, Wu HC, Huang W, Lei HY, Lai MD, Fausto N, Su IJ: Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology 2005, 41:761-770,Hepatology,41,pp761-770	Lily Hui-Ching Wang
2005	Chuang HC, Lay JD, Hsieh WC, Wang HC, Chang Y, Chuang SE, Su IJ.,2005,Chuang HC, Lay JD, Hsieh WC, Wang HC, Chang Y, Chuang SE, Su IJ. Epstein-Barr virus LMP1 inhibits the expression of SAP gene and Upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Blood 2005, 106:3090-3096,Blood,106,pp3090-3096	Lily Hui-Ching Wang

Research Interests
Title	Date	Attached file
	2010-10-14	File download

Educational background summary
School name	Country	Department	Degree	Starting date
				~

Service organization/unit	Title	Starting date
National Tsing Hua University	Assistant Professor	2010-08 ~
Biozentrum, University of Basel, Basel, Switzerland	Project Leader	2009-08 ~ 2010-07
Department of Cell Biology, Max-Planck Institute of Biochemistry, Martinsried	Postdoc	2006-06 ~ 2009-08
Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan	Postdoc	2004-07 ~ 2006-05
Department of Pathology, University of Washington, Seattle, Washington, USA	Research Scientist	2001-06 ~ 2001-09

College of Life Science, National Tsing Hua University

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