王翊青的個人資料 - 清華大學生命科學院

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姓名	王翊青
辦公室電話	03-5742003
辦公室	生科二館210室
E-mail

類別	專任師資
職稱	助理教授
單位別	生物科技研究所 / 生命科學系 / 學士班
現職	助理教授101年8月起
授課領域	基因轉譯調節、癌症生物學、肺臟發育與癌症生成
研究專長	基因轉譯調節、癌症生物學、肺臟發育與癌症生成

期刊論文一覽
年度	著作	著作人
2017	Sun L, Ren X, Wang IC, Pradhan A, Zhang Y, Flood HM, Han B, Whitsett JA, Kalin TV, Kalinichenko VV.,2017,The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice,Science Signaling,10,475,ppeaai8583- (SCI)	王翊青
2014	Wang IC, Ustiyan V, Zhang Y, Cai Y, Kalin TV, Kalinichenko VV.,2014,Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic KrasG12D,Oncogene,33,46,pp5391-5396 (SCI)	王翊青
2013	Balli D, Ustiyan V, Zhang Y, Wang IC, Masino AJ, Ren X, Whitsett JA, Kalinichenko VV, Kalin TV.,2013,Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition,EMBO J,32,2,pp231-44 (SCI)	王翊青
2012	Ustiyan V, Wert SE, Ikegami M, Wang IC, Kalin TV, Whitsett JA, Kalinichenko VV.,2012,Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways,Developmental Biology ,370,2,pp198-212 (SCI)	王翊青
2012	Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA, Kalinichenko VV.,2012,Foxm1 Mediates a Cross-talk between Kras/MAPK and Canonical Wnt Pathways during Development of Respiratory Epithelium.,MCB,32,19,pp3838-50 (SCI)	王翊青
2011	Bolte C, Zhang Y, Wang IC, Kalin TV, Molkentin JD, Kalinichenko VV. ,2011,Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development., PLoS One,6,7,ppe22217- (SCI)	王翊青
2010	Wang IC, Zhang Y, Snyder J, Sutherland M, Burhans MS, Shannon JM, Park HJ, Whitsett JA, Kalinichenko VV. ,2010,Increased Expression of Foxm1 Transcription Factor in Respiratory Epithelium Inhibits Lung Sacculation and Causes Clara Cell Hyperplasia. ,Dev. Biol.,347,2,pp301-314 (SCI)	王翊青
2009	Ustiyan V, Wang IC, Ren X, Zhang Y, Snyder J, Xu Y, Wert SE, Lessard JL, Kalin TV, Kalinichenko VV. ,2009,Forkhead Box M1 transcription factor is required for smooth muscle cell during embryonic development of blood vessels and esophagus. ,Dev. Biol. ,336,2,pp266-279 (SCI)	王翊青
2009	Wang IC, Meliton L, Ren X, Zhang Y, Balli D, Snyder J, Whitsett JA, Kalinichenoko VV, Kalin TV.,2009,Deletion of FoxM1 Transcription Factor from Lung Epithelial Cells Inhibits Pulmonary Tumorigenesis. ,PLoS One,4,8,ppe6609- (SCI)	王翊青
2008	Kalin TV, Wang IC, Meliton L, Zhang Y, Wert SE, Ren X, Snyder J, Bell SM, Graf L Jr, Whitsett JA, Kalinichenko VV. ,2008,Forkhead Box m1 transcription factor is required for perinatal lung function., Proc. Natl. Acad. Sci. USA,105,49,pp19329-19334 (SCI)	王翊青
2008	Wang IC, Chen YJ, Hughes DE, Ackerson T, Major ML, Costa RH, Tyner AL, Raychaudhuri P and Lau LF. ,2008,FOXM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness., J. of Biol. Chem.,283,30,pp20770-8 (SCI)	王翊青
2008	Wang IC, Meliton L, Ramakrishna S, Tretiakova M, Kalinichenko VV and Kalin TV. ,2008,The Forkhead BoxM1 Transcription Factor Accelerates Formation of Lung Tumors and Directly Induces Cox-2 Expression., Oncogene,27,30,pp4137-49 (SCI)	王翊青
2007	Yoshida Y, Wang IC, Yoder HM, Davidson NO and Costa RH. ,2007,The Forkhead Box M1 Transcription Factor is Required for Development and Growth of Mouse Colorectal Cancer. ,Gastroenterology,132,4,pp1420-31 (SCI)	王翊青
2007	Ramakrishna S, Kim IM, Petrovic V, Malin D, Wang IC, Kalin TV, Meliton L, Zhao YY, Qin Y, Malik AB, Costa RH, and Kalinichenko VV. ,2007,Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box m1 transcription factor. ,Dev Dyn.,236,4,pp1000-1013 (SCI)	王翊青
2007	Gusarova GA, Wang IC, Major ML, Kalinichenko VV, Ackerson T, Petrovic V, and Costa RH.,2007,A Cell Penetrating ARF Peptide Inhibitor of the Foxm1 Transcription Factor Is an Effective Treatment for Hepatocellular Carcinoma In Vivo. ,J Clin Invest.,117,1,pp99-111 (SCI)	王翊青
2006	Radhakrishnan SK, Bhat UG, Hughes DE, Wang IC, Costa RH and Gartel AL. ,2006,Identification of a chemical inhibitor of the oncogenic transcription factor Forkhead Box M1.,Cancer Res. ,66,19,pp9731-9735 (SCI)	王翊青
2006	Zhao YY, Gao X, Vogel S, Kalinichenko VV, Wang IC, Costa RH, and Malik AB.,2006,Endothelial Proliferation and Vascular Re-annealing Following Injury Induced by LPS. ,J Clin Invest.,116,9,pp2333-43 (SCI)	王翊青
2006	Kim IM, Ackerson T ,Ramakrishna S, Tretiakova M, Wang IC, Gusarova GA, Yoder HM, Costa RH, and Kalinichenko VV. ,2006,The Forkhead Box m1 Transcription Factor Is Essential for Proliferation of Tumor Cells during Development of Lung Cancer. ,Cancer Res.,66,4,pp2153-2161	王翊青
2006	Kalin TV, Wang IC, Ackerson T, Major ML, Detrisac C, Kalinichenko VV, Lyubimov A and Costa RH. ,2006,Increased Levels of the FoxM1 Transcription Factor Accelerate Development and Proliferation of Prostate Adenocarcinomas in both TRAMP and LADY Transgenic Mice. ,Cancer Res.,66,3,pp1712-1720 (SCI)	王翊青
2005	Wang IC, Chen YJ, Hughes DE, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, and Costa RH.,2005,Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase. ,Mol Cell Biol. ,25,24,pp10875-94 (SCI)	王翊青
2005	Costa RH, Kalinichenko VV, Tan Y, and Wang IC.,2005,The CAR Nuclear Receptor and Hepatocyte Proliferation. ,Hepatology,42,5,pp1004-1008 (SCI)	王翊青
2004	Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, Yoder HM, Kiyokawa H, Kaestner KH, Costa RH. ,2004,The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. ,Dev Biol.,276,1,pp74-88 (SCI)	王翊青
2003	Kalinichenko VV, Gusarova GA, Tan Y, Wang IC, Major ML, Wang X, Yoder HM, Costa RH. ,2003,Ubiquitous expression of the forkhead box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury. ,J Biol Chem.,278,39,pp37888-94 (SCI)	王翊青
2003	Chuang SM, Wang IC, Hwua YS, Yang JL.,2003,Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases.,Carcinogenesis,24,1,pp7-15 (SCI)	王翊青
2000	Chuang SM, Wang IC, Yang JL.,2000,Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium.,Carcinogenesis,21,7,pp1423-32 (SCI)	王翊青

研討會論文一覽
年度	會議期間	著作	著作人
2015	2015/08/10 2015/08/11	Wang, IC, Chiu YS, Chao SY, Chien HC, Li CC, Ip KU, Lee YC, Chen JK and Tsou TC.,2015,The role of transcription factor forkheadbox m1 in lung cancer,2015 Biomedical Research Symposium of National Health Research Institutes.,2015/08/10-2015/08/11 (其他)	王翊青
2014	2014/02/24 2014/02/27	Wang IC, Ustiyan V, Zhang Y, Cai Y, Kalin TV, Kalinichenko VV,2015,Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic KrasG12D,AACR Ras oncogene: From Biology to Therapy.,Lake Buena Vista, Florida.,2014/02/24-2014/02/27	王翊青
2013	2013/11/04 2013/11/06	Wang IC. ,2013,Foxm1 is essential for lung tumorigenesis induced by oncogenic KrasG12D.,IBMS-NHRI joint conference: International Conference on Inflammation, Cancer and Metabolic Diseases, Cancer Session,,Miaoli, Taiwan,2013/11/04-2013/11/06	王翊青
2013	2013/01/26 2013/01/25	Wang IC. ,2013,Foxm1 mediates Kras/MAPK signaling pathway in respiratory epithelium development and tumorigenesis.,3rd Toxicology General Meeting （TGM）,Taichung, Taiwan,2013/01/26-2013/01/25	王翊青
2012	2012/11/26 2012/11/26	Wang IC. ,2015,Foxm1 transcription factor is required for initiation of lung tumorigenesis by oncogenic K-Ras.,2012 NHRI-NTHU Joint Research Conference: Cancer Biology,,Miaoli, Taiwan.,2012/11/26	王翊青
2011	2011/08/14 2011/08/19	Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA and Kalinichenko VV.,Foxm1 Mediates a Cross-talk between Kras/MAPK and Canonical Wnt Signaling Pathways during Development of Respiratory Epithelium. ,Gordon Research Conference: Lung Development, Injury & Repair- Building and Rebuilding the Lung,Newport, Rhode Island,2011/08/14-2011/08/19 (其他)	王翊青
2011	2011/06/03 2011/06/03	Wang IC, Whitsett JA and Kalinichenko VV.,2011,The role of Foxm1 in Kras-induced lung tumorigenesis.,The National Lung Cancer Partnership 2011 Annual Meeting: Lung Cancer: Navigating the New Frontier,Chicago, IL,2011/06/03 (其他)	王翊青
2010	2010/08/08 2010/08/13	Wang IC, Zhang Y, Snyder J, Sutherland MJ, Burhans MS, Shannon JM, Whitsett JA and Kalinichenko VV. ,2010,Increased Expression of Foxm1 Transcription Factor in Respiratory Epithelium Inhibits Lung Sacculation and Caused Clara Cell Hyperplasia.,FASEB SUMMER RESEARCH CONFERENCES: The Lung Epithelium in Health and Disease,Saxtons River, Vermont.,2010/08/08-2010/08/13 (其他)	王翊青
2010	2010/01/11 2010/01/14	Wang IC, Kalin TV, Zhang Y, Snyder J, Whitsett JA and Kalinichenko VV. ,2012,The role of Foxm1 in lung cancer development: Transgenic gain of function and gene knock-out strategies.,AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy,Coronado, CA,2010/01/11-2010/01/14 (其他)	王翊青
2009	2009/04/18 2009/04/22	Kalin TV, Wang IC, Meliton L, Ren X, Whitsett JA, Kalinichenko VV.,2009,Deletion of Forkhead box M1 transcription factor from lung epithelial cells inhibits pulmonary tumorigenesis. ,AACR 100th Annual meeting,Denver, CO,2009/04/18-2009/04/22 (其他)	王翊青
2008	2008/08/03 2008/08/08	Kalin TV, Wang IC, Meliton L, Zhang Y, Wert SE, Ren X, Snyder J, Whitsett, JA, Kalinichenoko, VV.,2008,Forkhead Box M1 Transcription Factor is Required for Perinatal lung Function. ,FASEB SUMMER RESEARCH CONFERENCES: Lung Epithelium in Development and Disease,Saxtons River, Vermont,2008/08/03-2008/08/08 (其他)	王翊青
2008	2008/04/12 2008/04/16	Wang IC, Meliton L, Costa RH, Kalinichenko VV, Kalin TV. ,2008,Transgenic expression of the Forkhead box M1 transcription factor induces formation of lung tumors.,AACR 99th Annual meeting,San Diego, CA,2008/04/12-2008/04/16 (其他)	王翊青
2006	2007/07/22 2006/07/27	Gusarova GA, Wang IC, Major ML, Kalinichenko VV, Wang W, Yoder H, Ackerson T, Petrovic V, and Costa RH.,2006,A Cell Penetrating ARF Peptide Inhibitor of FoxM1 in Mouse Hepatocellular Carcinoma Treatment. ,FASEB SUMMER RESEARCH CONFERENCES: Liver Growth, Development and Disease,Snowmass Village, Colorado,2007/07/22-2006/07/27 (其他)	王翊青
2006	2006/07/22 2006/07/27	Wang IC, Hughes DE, Ackerson T, Major ML, and Costa RH.,2012,Diminished Progression into S-phase in Forkhead Box M1 Deficient Mammalian Cells is Associated with Reduced Expression of c-Jun NH2-Kinase 1 (JNK1) and ATF-2.,FASEB SUMMER RESEARCH CONFERENCES: Liver Growth, Development and Disease,Snowmass Village, Colorado,2006/07/22-2006/07/27 (其他)	王翊青
2006	2006/04/01 2006/04/05	Gusarova GA, Wang IC, Major ML, Kalinichenko VV, Ackerson T, Petrovic V, and Costa RH. ,2006,A cell penetrating ARF peptide inhibitor of the Foxm1 transcription factor is an effective treatment for hepatocellular carcinoma In Vivo. ,AACR 97th Annual meeting,Washington, D.C.,2006/04/01-2006/04/05 (其他)	王翊青
2004	2004/10/06 2004/10/10	Wang IC and Costa RH. ,2004,Mouse embryonic fibroblasts without the forkhead Box M1B (FoxM1B) transcription factor fail to execute mitosis and exhibit premature senescence., Cold Spring Harbor Laboratory Molecular Genetics of Aging Meeting.,Cold Spring Harbor, New York.,2004/10/06-2004/10/10	王翊青
2004	2004/08/07 2004/08/12	Kalinichenko VV, Krupczak-Hollis K, Wang X, Gusarova GA, Wang IC, Dennewitz MB, Kiyokawa H, Kaestner KH and Costa RH. ,2004,The mouse Foxm1b transcription factor is essential for development of bile ducts and hepatic vessels during liver morphogenesis.,FASEB SUMMER RESEARCH CONFERENCES: Mechanisms of Liver Growth, Development and Disease.,Snowmass Village, Colorado,2004/08/07-2004/08/12 (其他)	王翊青

參與活動服務一覽
類別	活動名稱	主題	參與人
(演講),(研討會)	The National Lung Cancer Partnership 2011 Annual Meeting	Role of Foxm1 in Kras-induced lung tumorigenesis.	王翊青

專利一覽
年度	專利類別	專利名稱	西元年月	專利人
2012	其他	“Method of inhibiting tumor cell proliferation”, a divisional application of US7635673, issued as U.S. Patent No. 7799896, September 21, 2010.	0000-00-00	王翊青 / University of Illinois Board of Trustee
2011	其他	“Methods of Inhibiting Tumor Cell Proliferation with FoxM1 siRNA”. European Patent (EP) Pub. No. EP1758999 B1, Mar 09, 2011	0000-00-00	王翊青 / University of Illinois Board of Trustee
2009	其他	“Methods of inhibiting tumor cell proliferation”. United States (US) Patent 7635673, December 22, 2009.	0000-00-00	王翊青 / University of Illinois Board of Trustee

研究計畫一覽
年度	計畫名稱	參與人	擔任之工作	計畫時間	補助/委託機構	附件檔案/參考連結
105	肺臟損傷修護及肺癌形成中細支氣管肺泡幹細胞的分裂調控	王翊青	PI	2016年08月 ~ 2019年07月	科技部優秀年輕學者研究計畫	/
103	轉錄因子 Foxm1 在上皮生長因子受體突變的肺癌中之角色	王翊青	主持人	2014年01月 ~ 2017年12月	國家衛生研究院研究發展獎助計畫	/
102	研究Forkhead家族蛋白在癌症起始及進程中之機轉及檢測	王翊青	子計畫主持人	2013年01月 ~ 2014年12月	清華大學頂尖研究中心整合型計畫	/
102	轉錄因子Forkhead Box M1在癌症發育中的角色	王翊青	主持人	2013年01月 ~ 2013年10月	國科會	/
102	探討 Foxm1 蛋白在肺癌起始及進展中的角色	王翊青	主持人	2013年08月 ~ 2016年07月	科技部優秀年輕學者研究計畫	/

校內榮譽一覽
得獎年度	獎項名稱	頒獎單位
2015	103學年度新進教師研究獎	國立清華大學生命科學院

校外榮譽一覽
得獎年度	獎項名稱	頒獎單位
2012	101年度國科會補助延攬特殊優秀人才獎勵	國科會
2009	Career Development Award	National Lung Cancer Partnership, USA
2001	Fellowship	Department of Molecular Genetics, College of Medicine, University of Illinois at Chicago

學歷一覽
學校名稱	國別	系所	學位	起迄年月
University of Illinois at Chicago	USA	Molecular Genetics	Ph.D.	2001年 ~ 2006年
National Tsing Hua University	Taiwan	Life Science	M.S.	1995年 ~ 1997年
Tung Hai University	Taiwan	Biology	B.S.	1991年10月 ~ 1995年06月

經歷一覽
服務機關	職稱	部門/系所	起迄年月
Cincinnati Children's Hospital Medical Center	Research Associate	Neonatology and Pulmonary Biology	2007年 ~ 2012年
University of Chicago	Research Professional Associate	Pulmonary and Critical Care	2007年 ~ 2007年
University of Illinois at Chicago	Postdoctoral Research Associate	Biochemistry and Molecular Genetics	2006年 ~ 2007年
Academia Sinica	Research Assistant	Institute of Biomedical Sciences	1999年 ~ 2001年

授課課程

必修
1. 分子與細胞生物學　
選修
1. 模式生物學　
2. 生醫研究小鼠模式

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