Yung-Jen ChuangPersonal data of - College of Life Science, National Tsing Hua University

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Name	Yung-Jen Chuang
Personal website	http://myjchuang.wixsite.com/yjc-lab

Category	Full-Time
Title	Professor
單位別	Institute of Bioinformatics and Structural Biology / Interdisciplinary Program of Life Science / Department of Medical Science
Discipline	Vascular Biology/ Functional Genomics/ Molecular Regulation
Research expertise	We are interested in vascular biology,including (1) the angiogenic cues during neurovascular interactions, (2) the process of tissue repair and vascular remodeling, (3) the tumor microenvironment.

Recent Publications
Year	Publication	Author
2019	2019, (SCI)	Yung-Jen Chuang
2018	Chao Shen⁠a⁠, Jixi Zhou⁠a⁠, Jinpeng Ruan⁠a, Yung-Jen Chuang⁠c, Chonggang Wang⁠,Zhenghong Zuo,2018,Generation of a Tg(cyp1a-12DRE: EGFP) transgenic zebrafish line as a rapid in vivo model for detecting dioxin-like compounds,Aquatic Toxicology,205,pp174-181 (SCI)	Yung-Jen Chuang
2018	2018,Development of a rapid and economic in vivo electrocardiogram platform for cardiovascular drug assay and electrophysiology research in adult zebrafish,8,1,pp15986- (SCI)	Yung-Jen Chuang
2018	2018,3,84,pp54-63 (SCI)	Yung-Jen Chuang
2018	Chang SJ, Liao EC, Yeo HY, Kuo WH, Chen HY, Tsai YT, Wei YS, Chen YJ, Wang YS, Li JM, Shih CC, Chan CH, Lai ZY, Chou HC, Chuang YJ* and Chan HL,2018*,Proteomic Investigating the Cooperative Lethal Effect of EGFR and MDM2 Inhibitors on Ovarian Carcinoma, (SCI)	Yung-Jen Chuang
2018	2018,12,Suppl 2,pp29- (SCI)	Yung-Jen Chuang
2017	2017,9,pp16281-16292 (SCI)	Yung-Jen Chuang
2017	2017, (SCI)	Yung-Jen Chuang
2017	2017, (SCI)	Yung-Jen Chuang
2017	2017, (SCI)	Yung-Jen Chuang
2017	Lai ZY, Yeo HY, Chen YT, Chang KM, Chen TC, Chuang YJ, Chang SJ.,2017,PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line,Oncotarget, (SCI)	Yung-Jen Chuang
2017	2017,4,pp494-502 (SCI)	Yung-Jen Chuang
2016	2016,23,1,pp59- (SCI)	Yung-Jen Chuang
2016	2016,Suppl 1,pp24-29 (SCI)	Yung-Jen Chuang
2016	2016, (SCI)	Yung-Jen Chuang
2015	2015,A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition,Biomed Research International.,2015, (SCI)	Yung-Jen Chuang
2014	2014,Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection,BMC Syst Biol.,8,S5,ppS6- (SCI)	Yung-Jen Chuang
2014	2014,The role of TGF-ß signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach,BMC Syst Biol.,8,1,pp116- (SCI)	Yung-Jen Chuang
2014	2014,Biomarker Discovery for Neuroendocrine Cervical Cancer. Electrophoresis,Electrophoresis,35,14,pp2039-2045 (SCI)	Yung-Jen Chuang
2014	2014,Essential Functional Modules for Pathogenic and Defensive Mechanisms in Candida albicans Infections,Biomed Research International.,2014,136130, (SCI)	Yung-Jen Chuang
2014	2014,On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio,PLoS One.,9,6,ppe97902- (SCI)	Yung-Jen Chuang
2013	2013,Expression of GOLM1 Correlates with Prognosis in Human Hepatocellular Carcinoma,Ann Surg Oncol. ,Suppl 3,ppS616-624 (SCI)	Yung-Jen Chuang
2013	2013,Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration,Cardiovasc Res,100,3,pp461-471 (SCI)	Yung-Jen Chuang
2013	2013,Synthesis and Evaluation of a Photoactive Probe with a Multivalent Carbohydrate for Capturing Carbohydrate-Lectin Interactions,Bioconjug Chem,24,11,pp1895-1906 (SCI)	Yung-Jen Chuang
2013	2013,Trivalent galactosyl-functionalized mesoporous silica nanoparticles as a target-specific delivery system for boron neutron capture therapy,Nanoscale,5,19,pp9412-9418 (SCI)	Yung-Jen Chuang
2013	2013,Stepwise Orthogonal Click Chemistry toward Fabrication of Paclitaxel/Galactose Functionalized Fluorescent Nanoparticles for HepG2 cell Targeting and Delivery,Bioconjug Chem,24,10,pp1698-1709 (SCI)	Yung-Jen Chuang
2013	2013,Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction stud,PLoS One,8,9,ppe72483- (SCI)	Yung-Jen Chuang
2013	2013,Identification of infection-related and defense-related genes via a dynamic host-pathogen interaction network using a C. Albicans - zebrafish infection model,Journal of Innate Immunity,5,2,pp137-152 (SCI)	Yung-Jen Chuang
2013	2013,A preclinical evaluation of antimycin a as a potential antilung cancer stem cell agent,Evid Based Complement Alternat Med.,	Yung-Jen Chuang
2013	2013, Interspecies protein-protein interaction network construction for characterization of host-pathogen interactions: a Candida albicans-zebrafish interaction ,BMC Syst Biol.,7,79, (SCI)	Yung-Jen Chuang
2013	2013,Diverse Hap43-independent functions of the Candida albicans CCAAT-binding complex,Eukaryot Cell.,12,6,pp804-815 (SCI)	Yung-Jen Chuang
2013	2013,Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish,PLoS One,8,6,ppe66613- (SCI)	Yung-Jen Chuang
2013	2013,PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish,Cardiovascular Research,97,3,pp443-453 (SCI)	Yung-Jen Chuang
2012	2012,Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc,Biomaterials,33,28,pp6728-6738 (SCI)	Yung-Jen Chuang
2012	2012,Adenylate kinase 4 promotes lung cancer metastasis through the downregulation of ATF3 and correlates with poor clinical outcome,Cancer Res,72,19,pp5119-5129 (SCI)	Yung-Jen Chuang
2012	2012,Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells,PLoS One,7,1,ppe30397- (SCI)	Yung-Jen Chuang
2012	2012,Significance of heparin binding to basic residues in homologous to amino terminus domain of hepatoma-derived growth factor and related proteins,Glycobiology,22,5,pp649-661	Yung-Jen Chuang
2012	2012,Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy., Chem Commun （Camb）,48,4,pp612-614 (SCI)	Yung-Jen Chuang
2011	2011,Robust H-infinity Observer-based Tracking Control of Stochastic Immune Systems under Environmental Disturbances and Measurement Noises,Asian J Control.,13,5,pp667-690 (SCI)	Yung-Jen Chuang
2011	2011,A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma,PLoS One.,6,8,ppe23452- (SCI)	Yung-Jen Chuang
2011	2011,Robust control of immune systems under noises: stochastic game approach,Springer Handbooks of Computational Statistics, (Others)	Yung-Jen Chuang
2011	2011,Soluble THSD7A Is an N-Glycoprotein That Promotes Endothelial Cell Migration and Tube Formation in Angiogenesis,PLoS One,6,12,ppe29000- (SCI)	Yung-Jen Chuang
2011	2011,Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development,Dev Dyn.,240,6,pp1412-1421 (SCI)	Yung-Jen Chuang
2011	2011,Baculovirus vectors for antiangiogenesis-based cancer gene therapy,Cancer Gene Ther., (SCI)	Yung-Jen Chuang
2011	Lin, R.Z., Wang, T.P., Hung, R.J., Chuang, Y.J., Chien, C.C. and Chang, H.Y. ,2011,Tumor-induced Endothelial Cell Apoptosis: Roles of NAD(P)H Oxidase-Derived Reactive Oxygen Species,Journal of Cellular Physiolog,226,7,pp1750-1762 (SCI)	Yung-Jen Chuang
2011	Kang, C.C., Chuang, Y.J., Tung, K.C., Cho, C.C., Tang, C.Y., Peng, S.C. and Wong, D.S.,2011,A Genetic Algorithm-based Boolean Delay Model of Intracellular Signal Transduction in Inflammation,BMC Bioinformatics,12,S1,ppS17- (SCI)	Yung-Jen Chuang
2010	Yang, S.K., Wang, Y.C., Chao, C.C., Chuang, Y.J., Lan, C.Y. and Chen, B.S. ,2010,Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNF alpha-induced inflammatory responses,BMC Medical Genomics,03,pp19- (SCI)	Yung-Jen Chuang
2010	Wang, C.H., Su, P.T., Du, X.Y., Kuo, M.W., Lin, C.Y., Yang, C.C., Chan, H.S., Chang, S.J., Kuo, C., Seo, K., Leung, L.L. and Chuang, Y.J.,2010,Thrombospondin Type I Domain Containing 7A (THSD7A) Mediates Endothelial Cell Migration and Tube Formation,Journal of Cellular Physiology,222,3,pp685-694 (SCI)	Yung-Jen Chuang
2010	Peng, S.C., Wong, D.S.H., Tung, K.C., Chen, Y.Y., Chao, C.C., Peng, C.H., Chuang, Y.J.* and Tang, C.Y. ,2010,Computing modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappa B signaling-induced gene expression responses in inflammation,BMC Bioinformatics ,11,pp308- (SCI)	Yung-Jen Chuang
2010	Lai, C.H., Lin, C.Y., Wu, H.T., Chan, H.S., Chuang, Y.J., Chen, C.T. and Lin, C.C. ,2010,Galactose Encapsulated Multifunctional Nanoparticle for HepG2 Cell Internalization, Advanced Functional Materials,20,22,pp3948-3958 (SCI)	Yung-Jen Chuang
2010	Huang, W.C., Hsieh, Y.S., Chen, I.H., Wang, C.H., Chang, H.W., Yang, C.C., Ku, T.H., Yeh, S.R. and Chuang, Y.J.,2010,Combined Use of MS-222 (Tricaine) and Isoflurane Extends Anesthesia Time and Minimizes Cardiac Rhythm Side Effects in Adult Zebrafish,Zebrafish,7,3,pp297-304 (SCI)	Yung-Jen Chuang
2010	Chao, C.C., Hsu, P.C., Jen, C.F., Chen, I.H., Wang, C.H., Chan, H.C., Tsai, P.W., Tung, K.C., Wang, C.H., Lan, C.Y., Chuang, Y.J.,2010,Zebrafish as a Model Host for Candida albicans Infection,Infection and Immunity ,78,6,pp2512-2521 (SCI)	Yung-Jen Chuang
2009	Chen, G.Y., Shiah, H.C., Su, H.J., Chen, C.Y., Chuang, Y.J., Lo, W.H., Huang, J.L., Chuang, C.K., Hwang, S.M. and Hu, Y.C. ,2009,Baculovirus Transduction of Mesenchymal Stem Cells Triggers the Toll-Like Receptor 3 Pathway,Journal of Virology,83,20,pp10548-10556 (SCI)	Yung-Jen Chuang
2008	Chen, M.L., Adak, A.K., Yeh, N.C., Yang, W.B., Chuang, Y.J., Wong, C.H., Hwang, K.C., Hwu, J.R.R., Hsieh, S.L. and Lin, C.C. ,2008,Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation,Angewandte Chemie-International Edition,47,45,pp8627-8630 (SCI)	Yung-Jen Chuang
2008	Chen, B.S., Yang, S.K., Lan, C.Y. and Chuang, Y.J.,2008,A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining,BMC Medical Genomics ,1,pp46- (SCI)	Yung-Jen Chuang
2008	Chen, B.S., Chang, C.H. and Chuang, Y.J.,2008,Robust model matching control of immune systems under environmental disturbances: Dynamic game approach,Journal of Theoretical Biology ,253,4,pp824-837 (SCI)	Yung-Jen Chuang
2006	Zhang, W.Q., Chuang, Y.J., Jin, T.Q., Swanson, R., Xiong, Y., Leung, L. and Olson, S.T.,2006,Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells,Cancer Research ,66,10,pp5047-5055 (SCI)	Yung-Jen Chuang

Patent overview
Year	Patent category	Patent title	Date (Year/Month)	Patent owner
2017	其他		2017-02-00	Yung-Jen Chuang
2014	其他	Devices and methods for tracking moving objects （USA Patent）	2014-12-00	Yung-Jen Chuang
2014	其他	追蹤移動物件之裝置與方法（Taiwan Patent）	2014-11-00	Yung-Jen Chuang
2014	其他	Transparent zebrafish and preparation method thereof （USA Patent）	2014-04-00	Yung-Jen Chuang

Honors & Awards (NTHU)
Year of award	Name of award	Awarded by
103	Teaching award	National Tsing Hua University
100	Teaching award	College of Life Science, NTHU
99	Teaching award	College of Life Science, NTHU
96	Teaching award	National Tsing Hua University

Educational background summary
School name	Country	Department	Degree	Starting date
University of Illinois-Chicago	USA	Bioengineering	Ph.D.	1994-09 ~ 2000-06
National Tsing Hua University	Taiwan	Chemical Engineering	B.Sc.	1985-09 ~ 1989-06

Experiences
Service organization/unit	Title	Department	Starting date
			2014-08 ~ 2016-08
			2014-02 ~ 2014-07
			2013-08 ~
National Tsing Hua University	Associate Professor	Department of Medical Science	2010-08 ~ 2013-07
National Tsing Hua University	Assistant Professor	Department of Life Science	2004-08 ~ 2010-07
Stanford University	Postdoc fellow	Medicine - Hematology	2000-09 ~ 2004-05

Subject

必修
1. 生命科學一　
2. 人體生理與解剖學　
3. 轉譯醫學　
選修
1. 血管生物學特論二　
2. 血管生物學特論一

College of Life Science, National Tsing Hua University

Subject

標準版RSs 2.x套裝

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